Bioscience

Biography

David Pastre is currently the Head of the SABNP Laboratory (INSERM unit U1204) and Professor at the University of Evry. He after studying Physics and Optics at the University of Montpellier, has developed a set up to collect cathodoluminescence near field. During a Post-doctoral fellowship at the University of Virginia (2000-2001), he designed a method to observe living mammalian cells at high-resolution with a scanning ion conductance microscope. As a Teacher-Researcher at the University of Evry, he deciphered the mechanisms leading to DNA absorption on mica and studied the formation of DNA and RNA/protein complexes on mica by atomic force microscopy. He is currently investigating, at the cellular and molecular levels, the dynamics and structure of RNA/protein complexes involved in the control of protein expression and the mechanisms which regulate microtubule dynamics. He also continues to develop novel methods to explore cellular and molecular processes.

Abstract

Abstract : Visualization and quantification of protein interactions along microtubules in mammalian cells