Biography
Biography: Ganapathy Sivakumar
Abstract
Colchicine is one of the most important alkaloid-based antigout drugs with anticancer potential which is unique to Colchicaceae. Gloriosa superba L is a very successful commercial source of plant-based pharmaceutical colchicine. However, high colchicine production is challenging and the cultivation is labor-intensive, time consuming, and expensive. Indeed, there is no bio-manufacturing technology for the production of plant-based colchicine. A new biotechnological bio-rhizome engineering platform is emerging from G. superba. Author will discuss recent advances in bio-rhizome to bio-manufacture therapeutic colchicine.